Organoid

Original Article

September 25, 2024

The regenerative capacity of hepatocyte organoids following long-term cryopreservation in Republic of Korea

Sun A Ock, Seo-Yeon Kim, Young-Im Kim, et al.

Organoid. 2024;4:e9.

Background: Hepatocyte organoids (HOs) are more functionally versatile than bile duct epithelial cell organoids, but have a shorter lifespan. This limitation has been improved by optimizing culture methods, but could...

Review Article

August 25, 2024

Transformative potential of three-dimensional bioprinting technology for advanced organoid research

Jungbin Yoon, Goeun Yoon, Jinah Jang

Organoid. 2024;4:e8.

Organoid research has emerged as a transformative field in biomedicine, focusing on the in vitro development of 3-dimensional (3D) structures that mimic human organs. Derived from various types of stem...

Review Article

July 25, 2024

Optical coherence tomography and its recent applications for three-dimensional imaging of organoids

Woo June Choi, Eun Seo Choi

Organoid. 2024;4:e7.

An organoid is a self-organizing, miniaturized model of an organ that recapitulates the architecture and physiology of the tissue of origin. With their high resemblance to the structure and function...

Review Article

June 25, 2024

Advances in cardiac organoid technology: current trends and standardized quality assessment for toxicity testing in preclinical models

Su-Jin Lee, Hyang-Ae Lee

Organoid. 2024;4:e6.

Cardiotoxicity is a prominent cause of drug withdrawal, impacting drug development during preclinical and clinical phases, as well as post-market approval. Traditional 2-dimensional cell culture models, despite being resource-rich, suffer...

Review Article

May 25, 2024

Developments in endoderm and pancreatic β-cell differentiation from human pluripotent stem cells

Dong Hyeon Lee, Hwajung Choo, Hyo Yi Choi, et al.

Organoid. 2024;4:e5.

Human pluripotent stem cells (hPSCs) can differentiate into any cell type in the body, including cells or tissues from ectodermal, mesodermal, or endodermal lineages. Type 1 diabetes is characterized by...

Review Article

April 25, 2024

Mimicking microbone tissue by 3-dimensional printing

Seung Yeon Lee, Jin Woo Lee

Organoid. 2024;4:e4.

Bones are mineralized connective tissues composed of osteoclasts, osteoblasts, and osteocytes. While bone is one of the few tissues that can regenerate in adulthood, its regeneration is limited in the...

Original Article

March 25, 2024

ERdj5-mediated regulation of proliferation and differentiation in colon organoids under inflammatory stress

Hyunjin Jeong, Jaewon Cho, Hyun-Jeong Ko

Organoid. 2024;4:e3.

Background: Endoplasmic reticulum (ER) stress is resolved by ERdj5, which functions as a disulfide reductase. In a previous study, we confirmed that ERdj5 was not indispensable for the formation of...

Original Article

February 25, 2024

Modelling Fabry disease with kidney organoids derived from human embryonic stem cells using CRISPR-Cas9 mediated gene editing

Su Jeong Lee, Kyung Jin Lee, Joo Hyun Jee, et al.

Organoid. 2024;4:e2.

Using gene editing to generate a nephron organoid model which recapitulates the hallmarks of human kidney disease is an attractive strategy, especially due to the potential for drug discovery in...

Review Article

January 25, 2024

Telencephalic organoids as model systems to study cortical development and diseases

Woo Sub Yang, Ferdi Ridvan Kiral, In-Hyun Park

Organoid. 2024;4:e1.

The telencephalon is the largest region of the brain and processes critical brain activity. Despite much progress, our understanding of the telencephalon’s function, development, and pathophysiological processes remains largely incomplete....

Current Issue: Volume 4; 2024

Organoid

Online ISSN: 2765-205X

MOST VIEWED MOST CITED

4,144	Modelling Fabry disease with kidney organoids derived from human embryonic stem cells using CRISPR-Cas9 mediated gene editing
7,276	Three-dimensional cardiac organoid formation accelerates the functional maturation of human induced pluripotent stem cell-derived cardiomyocytes
3,622	ERdj5-mediated regulation of proliferation and differentiation in colon organoids under inflammatory stress
4,248	Telencephalic organoids as model systems to study cortical development and diseases
8,898	Recent advances and challenges in organoid-on-a-chip technology

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Cited By 6	Progress, prospects, and limitations of organoid technology
Cited By 5	Recent advances and challenges in organoid-on-a-chip technology
Cited By 4	Three-dimensional cardiac organoid formation accelerates the functional maturation of human induced pluripotent stem cell-derived cardiomyocytes
Cited By 3	The application of intestinal organoids and their co-culture systems in the study of gastrointestinal diseases
Cited By 2	A brain metastasis model for breast cancer using human embryonic stem cell-derived cerebral organoids

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