Organoid

Review Article

November 25, 2023

Genome editing for engineering stem cell-derived pancreatic β cells: recent trends and future perspectives

Seeun Jang, Siyoon Shin, Yujin Jeong, et al.

Organoid. 2023;3:e17.

Rapid advancements in biotechnology have enabled the development of new therapeutic modalities for refractory diseases. Among these, stem cell-derived β (SC-β) cells are emerging as next-generation therapeutics for diabetes. However,...

Original Article

October 25, 2023

Optimization of Matrigel concentration for salivary gland organoid culture

Eunhoo Choi, Sangho Roh

Organoid. 2023;3:e14.

Background: Research on salivary gland tissue is important, both for maintaining good oral health and for understanding the properties and functions of secretory cells with similar developmental mechanisms and functions....

Review Article

September 25, 2023

Natural biopolymer-based hydrogels as designer matrices for organoid cultures

Yun Kee Jo

Organoid. 2023;3:e13.

Matrigel, a mouse sarcoma-derived extract, is considered the gold standard for organoid cultures. However, it has several drawbacks, including inconsistent and ill-defined composition, varying quality between batches, and potential cancer-related...

Review Article

August 25, 2023

Inkjet-based bioprinting for tissue engineering

Ju An Park, Yunji Lee, Sungjune Jung

Organoid. 2023;3:e12.

Inkjet bioprinting, a derivative of traditional inkjet technology, is gaining recognition in the fields of life sciences and tissue engineering due to its ability to produce picoliter volume droplets at...

Original Article

July 25, 2023

A novel method for generating induced pluripotent stem cell (iPSC)-derived alveolar organoids: a comparison of their ability depending on iPSC origin

Min Jae Lim, Ayoung Jo, Sung-Won Kim

Organoid. 2023;3:e11.

Background: Alveolar organoids may be useful tools in drug discovery for lung diseases, such as chronic obstructive pulmonary disease, and for studying the effects of respiratory viruses, such as severe...

Review Article

June 25, 2023

Kidney organoids: development and applications

Hye-Youn Kim, Seyoung Yu, Yo Jun Choi, et al.

Organoid. 2023;3:e10.

Since the first publication on generating kidney-like cell aggregates from pluripotent stem cells, various modifications have been made to develop more complex and detailed kidney structures. In contrast to earlier...

Original Article

May 25, 2023

Suspension-cultured taste bud organoids recapitulate in vivo taste buds

Anish Ashok Adpaikar, Jong-Min Lee, Han-Sung Jung

Organoid. 2023;3:e9.

Background: Taste buds are a complex organ and require a plethora of growth factors for their development, homeostasis, and regeneration. Taste bud organoids provide a platform for understanding their development,...

Original Article

February 25, 2023

A polymer-based artificial microenvironment for enhancing cell adhesion

Su-Han Lee, Hye Bin Park, Sang-Keun Sung, et al.

Organoid. 2023;3:e8.

An efficient platform capable of cell adhesion needs to be developed to understand cell activities such as cell differentiation, diffusion, and migration. The basic sequence of cell adhesion involves cells...

Review Article

April 25, 2023

Development of otic organoids and their current status

Hantai Kim, Young Sun Kim, Yeon Ju Kim, et al.

Organoid. 2023;3:e7.

The inner ear is responsible for both hearing and balance in the body, and since the initial development of otic (inner ear) organoids from mouse pluripotent stem cells (PSCs) in...

Original Article

March 25, 2023

Tumor spheroid-based and microtumor-based vascularized models for replicating the vascularized tumor microenvironment

Jiyoung Song, Jihoon Ko, Nakwon Choi, et al.

Organoid. 2023;3:e6.

Background Tumor vasculature is a crucial pathway for supplying nutrients and oxygen to tumors during their progression, as well as facilitating the delivery of anticancer drugs or immunotherapeutic agents. Microfluidic technology...

Review Article

April 25, 2023

Microengineered organoids: reconstituting organ-level functions in vitro

Sunho Park, Harshita Sharma, Woochan Kim, et al.

Organoid. 2023;3:e5.

In vitro miniaturized organoids are innovative tools with varying applications in biomedical engineering, such as drug testing, disease modeling, organ development studies, and regenerative medicine. However, conventional organoid development has...

Original Article

March 25, 2023

Small molecule-induced destabilization of β-catenin and RAS is the ideal strategies for suppressing colorectal cancer

Yonghyo Kim, Myoung-Hee Kang, Geon-Woo Kim, et al.

Organoid. 2023;3:e4.

Background: Mutations of adenomatous polyposis coli (APC) and KRAS play essential roles in the development of colorectal cancer (CRC) by forming an abnormal colon morphology. Despite intensive efforts to discover...

Original Article

February 25, 2023

One-step achievement of tumor spheroid-induced angiogenesis in a high-throughput microfluidic platform: one-step tumor angiogenesis platform

Seonghyuk Park, Youngtaek Kim, Jihoon Ko, et al.

Organoid. 2023;3:e3.

Research on the development of anti-cancer drugs has progressed, but the low reliability of animal experiments due to biological differences between animals and humans causes failures in the clinical process....

Review Article

January 25, 2023

Induced pluripotent stem cell-derived hematopoietic stem and progenitor cells: potential, challenges, and future perspectives

Myoung Hee Han, Da-Hyun Kim, Kyung-Rok Yu

Organoid. 2023;3:e2.

Hematopoietic stem and progenitor cells (HSPCs) are responsible for the lifetime dynamics of hematopoiesis, as they are well known for their self-renewing ability and multipotency to differentiate into all types...

Review Article

January 25, 2023

Engineered adipose tissue platforms: recent breakthroughs and future perspectives

Heejeong Yoon, Tae-Eun Park

Organoid. 2023;3:e1.

As overweight and obesity rates have increased worldwide, the prevalence of metabolic disorders has also grown. Due to the lack of physiologically relevant adipose tissue platforms, research in adipose tissue...

Current Issue: Volume 3; 2023

Genome editing for engineering stem cell-derived pancreatic β cells: recent trends and future perspectives Seeun Jang, Siyoon Shin, Yujin Jeong, et al. Organoid. 2023;3:e17. Review Article Nov 25, 2023 Full text PubReader ePub PDF	Optimization of Matrigel concentration for salivary gland organoid culture Eunhoo Choi, Sangho Roh Organoid. 2023;3:e14. Original Article Oct 25, 2023 Full text PubReader ePub PDF
Natural biopolymer-based hydrogels as designer matrices for organoid cultures Yun Kee Jo Organoid. 2023;3:e13. Review Article Sep 25, 2023 Full text PubReader ePub PDF	Inkjet-based bioprinting for tissue engineering Ju An Park, Yunji Lee, Sungjune Jung Organoid. 2023;3:e12. Review Article Aug 25, 2023 Full text PubReader ePub PDF
A novel method for generating induced pluripotent stem cell (iPSC)-derived alveolar organoids: a comparison of their ability depending on iPSC origin Min Jae Lim, Ayoung Jo, Sung-Won Kim Organoid. 2023;3:e11. Original Article Jul 25, 2023 Full text PubReader ePub PDF	Kidney organoids: development and applications Hye-Youn Kim, Seyoung Yu, Yo Jun Choi, et al. Organoid. 2023;3:e10. Review Article Jun 25, 2023 Full text PubReader ePub PDF
Suspension-cultured taste bud organoids recapitulate in vivo taste buds Anish Ashok Adpaikar, Jong-Min Lee, Han-Sung Jung Organoid. 2023;3:e9. Original Article May 25, 2023 Full text PubReader ePub PDF Supplementary Material	Microengineered organoids: reconstituting organ-level functions in vitro Sunho Park, Harshita Sharma, Woochan Kim, et al. Organoid. 2023;3:e5. Review Article Apr 25, 2023 Full text PubReader ePub PDF
Development of otic organoids and their current status Hantai Kim, Young Sun Kim, Yeon Ju Kim, et al. Organoid. 2023;3:e7. Review Article Apr 25, 2023 Full text PubReader ePub PDF	Small molecule-induced destabilization of β-catenin and RAS is the ideal strategies for suppressing colorectal cancer Yonghyo Kim, Myoung-Hee Kang, Geon-Woo Kim, et al. Organoid. 2023;3:e4. Original Article Mar 25, 2023 Full text PubReader ePub PDF
Tumor spheroid-based and microtumor-based vascularized models for replicating the vascularized tumor microenvironment Jiyoung Song, Jihoon Ko, Nakwon Choi, et al. Organoid. 2023;3:e6. Original Article Mar 25, 2023 Full text PubReader ePub PDF Supplementary Material	A polymer-based artificial microenvironment for enhancing cell adhesion Su-Han Lee, Hye Bin Park, Sang-Keun Sung, et al. Organoid. 2023;3:e8. Original Article Feb 25, 2023 Full text PubReader ePub PDF
One-step achievement of tumor spheroid-induced angiogenesis in a high-throughput microfluidic platform: one-step tumor angiogenesis platform Seonghyuk Park, Youngtaek Kim, Jihoon Ko, et al. Organoid. 2023;3:e3. Original Article Feb 25, 2023 Full text PubReader ePub PDF	Engineered adipose tissue platforms: recent breakthroughs and future perspectives Heejeong Yoon, Tae-Eun Park Organoid. 2023;3:e1. Review Article Jan 25, 2023 Full text PubReader ePub PDF
Induced pluripotent stem cell-derived hematopoietic stem and progenitor cells: potential, challenges, and future perspectives Myoung Hee Han, Da-Hyun Kim, Kyung-Rok Yu Organoid. 2023;3:e2. Review Article Jan 25, 2023 Full text PubReader ePub PDF

Organoid

Online ISSN: 2765-205X

4,668	A novel method for the isolation of CD45-positive and CD45-negative cells from malignant pleural effusion
6,619	Trends in the global organoid technology and industry: from organogenesis in a dish to the commercialization of organoids
2,861	Induced pluripotent stem cell-derived hematopoietic stem and progenitor cells: potential, challenges, and future perspectives
8,978	Human brain organoids in Alzheimer’s disease
2,216	Engineered adipose tissue platforms: recent breakthroughs and future perspectives

Cited By 5	Human brain organoids in Alzheimer’s disease
Cited By 3	Recent advances and challenges in organoid-on-a-chip technology
Cited By 2	Engineered models for studying blood-brain-barrier-associated brain physiology and pathology
Cited By 2	Progress, prospects, and limitations of organoid technology
Cited By 1	Lung organoids: target cells for understanding respiratory diseases