Organoid

Review Article

July 10, 2021

Trends in the global organoid technology and industry: from organogenesis in a dish to the commercialization of organoids

Hanbyeol Lee, Jeong Suk Im, Da Bin Choi, et al.

Organoid. 2021;1:e11.

Animal models have been standard methods for non-clinical research in drug development for decades. However, many drugs that have shown satisfactory results in non-clinical studies have failed in the clinical...

Review Article

June 19, 2021

Engineered models for studying blood-brain-barrier-associated brain physiology and pathology

Hong Nam Kim

Organoid. 2021;1:e10.

The blood-brain barrier (BBB) is a transport barrier that suppresses the translocation of potentially harmful substances to the brain tissue. Although the BBB is known to be associated with many...

Review Article

October 19, 2021

Single-cell transcriptomics of lung organoids

Ye Na Song, Man Ryul Lee

Organoid. 2021;1:e9.

The in vitro application of human pluripotent stem cell- or adult stem cell-derived lung organoids has the potential to revolutionize lung disease research, but there are several limitations in the...

Review Article

May 30, 2021

Disease modeling and drug screening using human airway organoids: a systematic review

Do Hyun Kim, Sung Won Kim

Organoid. 2021;1:e8.

Increasing levels of fine environmental dust particles due to industrialization and emerging respiratory illnesses, such as coronavirus disease 2019, pose serious threats to human life. The use of organoids for...

Original Article

September 30, 2021

Optimizing a three-dimensional spheroid clearing method for the imaging-based evaluation of cardiotoxicity

Ji Hye Park, Jaemeun Lee, Sun-Hyun Park, et al.

Organoid. 2021;1:e7.

Toxicity evaluation based on two-dimensional cell culture shows differences from clinical results and has the disadvantage of not accurately reflecting cell-to-cell cross-signaling. Since almost all cells in the human body...

Review Article

April 10, 2021

Therapeutic applications of three-dimensional organoid models in lung cancer

Chang Dong Yeo, Young-Pil Yun, Dong Hyuck Ahn, et al.

Organoid. 2021;1:e6.

Lung cancer, which remains a major cause of mortality worldwide, is a histologically diverse condition and demonstrates substantial phenotypic and genomic diversity among individual patients, manifesting as both intertumoral and...

Review Article

March 27, 2021

Human brain organoids in Alzheimer’s disease

You Jung Kang, Hansang Cho

Organoid. 2021;1:e5.

Alzheimer’s disease (AD) is a progressive neurological disorder that typically involves neuronal damage leading to the deterioration of cognitive and essential body functions in aging brains. Major signatures of AD...

Review Article

February 27, 2021

Lung organoids: target cells for understanding respiratory diseases

Jooyeon Lee, Se-Ran Yang

Organoid. 2021;1:e4.

Human respiratory disease research currently lacks in vitro models that recapitulate most of the physiology and architecture of the lung. Furthermore, the complex composition and structure of the lung, as...

Review Article

January 21, 2021

Endoplasmic reticulum stress and organoids

Rashedul Alam, Mohammad Mamun Ur Rashid, Mohammad Fazlul Kabir, et al.

Organoid. 2021;1:e3.

Organoids represent an advanced tool in cell biology and have redefined biomedical research. Organoids are ideal for studies of biological processes, pharmacological studies, and therapeutic research to imitate pathological processes...

Editorial

January 20, 2021

Welcome to Organoid: a new and innovative journal

Seung Joon Kim, Kyung-Sun Kang, Hyung-Ryong Kim

Organoid. 2021;1:e2.

Presidential Message

January 20, 2021

Presidential message

Hyung-Ryong Kim

Organoid. 2021;1:e1.

Current Issue: Volume 1; 2021

This archive contains links to the full-text of all issues of Organoid.

Current issue

Volume 1; 2021

All issues

Vol. 1
2021

v.1
Jan 2021

Organoid

Online ISSN: 2765-205X

4,279	Lung organoids: target cells for understanding respiratory diseases
3,331	Endoplasmic reticulum stress and organoids
2,116	Human brain organoids in Alzheimer’s disease
1,429	Welcome to Organoid: a new and innovative journal
1,456	Presidential message