Organoid

Original Article

July 25, 2026

Single-cell profiling of patient-derived ovarian cancer organoids identifies epithelial states enriched after acute tamoxifen exposure

Sangwon Park, Seungeun Lee, Minsung Kim, et al.

Organoid. 2026;6:e7.

Background: Tamoxifen is used for hormone receptor-positive breast cancer, but its activity and response determinants in ovarian cancer remain incompletely defined. Integrating patient-derived organoids (PDOs) with single-cell RNA sequencing (scRNA-seq)...

Review Article

June 25, 2026

Recent advances and current limitations of vascular organoids

Nahyun Yoon, Seongmin Kim, Jong-Chan Park

Organoid. 2026;6:e6.

Organoids are widely used experimental models for investigating human tissue development, disease mechanisms, and therapeutic responses because their 3-dimensional (3D) architecture more closely resembles in vivo tissue organization than conventional...

Review Article

May 25, 2026

Organoids for evaluating chronobiotics and functional foods

Miri Park, Donghwan Kim

Organoid. 2026;6:e5.

The intestinal epithelium functions as a peripheral circadian oscillator that regulates nutrient absorption, barrier integrity, and immune signaling across a 24-hour cycle. Chronic circadian disruption has been implicated in metabolic...

Original Article

April 25, 2026

Single-cell time-course transcriptomic analysis reveals epithelial remodeling in human gastric corpus organoids after WNT pathway perturbation

Na-Yeon Kim, Seung-Pyo Hong, Dakyung Lee, et al.

Organoid. 2026;6:e4.

Background: WNT signaling is essential for gastric epithelial stem cell homeostasis. However, the temporal transcriptional dynamics following WNT/RSPO perturbation in human gastric organoids remain unclear. Methods: Human gastric corpus organoids derived...

Original Article

March 25, 2026

Integrative transcriptomics defines the culture-imposed identity of ovarian cancer organoids

Seonghyeok Woo, Dong-Ju Shin, Jin-Ku Lee

Organoid. 2026;6:e3.

Background: Patient-derived organoids have transformed preclinical oncology by providing three-dimensional tumor models that preserve genomic fidelity and heterogeneous drug responses. However, whether these models faithfully recapitulate the transcriptomic identity of...

Review Article

February 25, 2026

Epithelial plasticity in lung cancer evolution: insights from organoids

Sungji Moon, Dakyung Lee, Jaeyong Choi, et al.

Organoid. 2026;6:e2.

Lung cancer remains the leading cause of cancer-related mortality and is often diagnosed at an advanced stage, limiting opportunities for early intervention. In vitro 3-dimensional lung organoid cultures recapitulate key...

Review Article

January 25, 2026

Lung organoid platforms for modeling severe acute respiratory syndrome coronavirus 2 infection: advances, limitations, and future directions

Geon-Woo Kim, Yong-Hee Cho

Organoid. 2026;6:e1.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection begins when the viral spike protein binds angiotensin-converting enzyme 2 (ACE2) on airway and alveolar epithelial cells and is activated by transmembrane...

Current Issue: Volume 6; 2026

This archive contains links to the full-text of all issues of Organoid.

Current issue

Volume 6; 2026

All issues

Vol. 6
2026

v.6
2026

Vol. 5
2025

v.5
2025

Vol. 4
2024

v.4
2024

Vol. 3
2023

v.3
2023

Vol. 2
2022

v.2
2022

Vol. 1
2021

v.1
Jan 2021

Organoid

Online ISSN: 2765-205X

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