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Review Article

September 25, 2023


Natural biopolymer-based hydrogels as designer matrices for organoid cultures
Yun Kee Jo
Organoid. 2023;3:e13.

Matrigel, a mouse sarcoma-derived extract, is considered the gold standard for organoid cultures. However, it has several drawbacks, including inconsistent and ill-defined composition, varying quality between batches, and potential cancer-related...

Review Article

August 25, 2023


Inkjet-based bioprinting for tissue engineering
Ju An Park, Yunji Lee, Sungjune Jung
Organoid. 2023;3:e12.

Inkjet bioprinting, a derivative of traditional inkjet technology, is gaining recognition in the fields of life sciences and tissue engineering due to its ability to produce picoliter volume droplets at...

Original Article

July 25, 2023


A novel method for generating induced pluripotent stem cell (iPSC)-derived alveolar organoids: a comparison of their ability depending on iPSC origin
Min Jae Lim, Ayoung Jo, Sung-Won Kim
Organoid. 2023;3:e11.

Background: Alveolar organoids may be useful tools in drug discovery for lung diseases, such as chronic obstructive pulmonary disease, and for studying the effects of respiratory viruses, such as severe...

Review Article

June 25, 2023


Kidney organoids: development and applications
Hye-Youn Kim, Seyoung Yu, Yo Jun Choi, et al.
Organoid. 2023;3:e10.

Since the first publication on generating kidney-like cell aggregates from pluripotent stem cells, various modifications have been made to develop more complex and detailed kidney structures. In contrast to earlier...

Original Article

May 25, 2023


Suspension-cultured taste bud organoids recapitulate in vivo taste buds
Anish Ashok Adpaikar, Jong-Min Lee, Han-Sung Jung
Organoid. 2023;3:e9.

Background: Taste buds are a complex organ and require a plethora of growth factors for their development, homeostasis, and regeneration. Taste bud organoids provide a platform for understanding their development,...

Original Article

February 25, 2023


A polymer-based artificial microenvironment for enhancing cell adhesion
Su-Han Lee, Hye Bin Park, Sang-Keun Sung, et al.
Organoid. 2023;3:e8.

An efficient platform capable of cell adhesion needs to be developed to understand cell activities such as cell differentiation, diffusion, and migration. The basic sequence of cell adhesion involves cells...

Review Article

April 25, 2023


Development of otic organoids and their current status
Hantai Kim, Young Sun Kim, Yeon Ju Kim, et al.
Organoid. 2023;3:e7.

The inner ear is responsible for both hearing and balance in the body, and since the initial development of otic (inner ear) organoids from mouse pluripotent stem cells (PSCs) in...

Original Article

March 25, 2023


Tumor spheroid-based and microtumor-based vascularized models for replicating the vascularized tumor microenvironment
Jiyoung Song, Jihoon Ko, Nakwon Choi, et al.
Organoid. 2023;3:e6.

Background Tumor vasculature is a crucial pathway for supplying nutrients and oxygen to tumors during their progression, as well as facilitating the delivery of anticancer drugs or immunotherapeutic agents. Microfluidic technology...

Review Article

April 25, 2023


Microengineered organoids: reconstituting organ-level functions in vitro
Sunho Park, Harshita Sharma, Woochan Kim, et al.
Organoid. 2023;3:e5.

In vitro miniaturized organoids are innovative tools with varying applications in biomedical engineering, such as drug testing, disease modeling, organ development studies, and regenerative medicine. However, conventional organoid development has...

Original Article

March 25, 2023


Small molecule-induced destabilization of β-catenin and RAS is the ideal strategies for suppressing colorectal cancer
Yonghyo Kim, Myoung-Hee Kang, Geon-Woo Kim, et al.
Organoid. 2023;3:e4.

Background: Mutations of adenomatous polyposis coli (APC) and KRAS play essential roles in the development of colorectal cancer (CRC) by forming an abnormal colon morphology. Despite intensive efforts to discover...

Original Article

February 25, 2023


One-step achievement of tumor spheroid-induced angiogenesis in a high-throughput microfluidic platform: one-step tumor angiogenesis platform
Seonghyuk Park, Youngtaek Kim, Jihoon Ko, et al.
Organoid. 2023;3:e3.

Research on the development of anti-cancer drugs has progressed, but the low reliability of animal experiments due to biological differences between animals and humans causes failures in the clinical process....

Review Article

January 25, 2023


Induced pluripotent stem cell-derived hematopoietic stem and progenitor cells: potential, challenges, and future perspectives
Myoung Hee Han, Da-Hyun Kim, Kyung-Rok Yu
Organoid. 2023;3:e2.

Hematopoietic stem and progenitor cells (HSPCs) are responsible for the lifetime dynamics of hematopoiesis, as they are well known for their self-renewing ability and multipotency to differentiate into all types...

Review Article

January 25, 2023


Engineered adipose tissue platforms: recent breakthroughs and future perspectives
Heejeong Yoon, Tae-Eun Park
Organoid. 2023;3:e1.

As overweight and obesity rates have increased worldwide, the prevalence of metabolic disorders has also grown. Due to the lack of physiologically relevant adipose tissue platforms, research in adipose tissue...
Current Issue
Volume 3; 2023
Human brain organoids in Alzheimer’s disease
You Jung Kang, Hansang Cho
Organoid. 2021;1:e5.

Review Article

Mar 15, 2021
Recent advances and challenges in organoid-on-a-chip technology
Intan Rosalina Suhito, Tae-Hyung Kim
Organoid. 2022;2:e4.

Review Article

Apr 25, 2022
Engineered models for studying blood-brain-barrier-associated brain physiology and pathology
Hong Nam Kim
Organoid. 2021;1:e10.

Review Article

Jun 15, 2021
The application of intestinal organoids and their co-culture systems in the study of gastrointestinal diseases
Panida Sittipo, Yun Kyung Lee
Organoid. 2022;2:e3.

Review Article

Jan 25, 2022
Glioblastoma organoid technology: an emerging preclinical models for drug discovery
Don Carlo Ramos Batara, Shuchang Zhou, Moon-Chang Choi, et al.
Organoid. 2022;2:e7.

Review Article

Feb 25, 2022
Progress, prospects, and limitations of organoid technology
Jin Hee Park, Do Gyeung Byeun, Jung Kyu Choi
Organoid. 2022;2:e9.

Review Article

Apr 25, 2022
Toward brain organoid-based precision medicine in neurodegenerative diseases
Jong-Chan Park, Inhee Mook-Jung
Organoid. 2022;2:e21.

Review Article

Oct 25, 2022
Lung organoids: target cells for understanding respiratory diseases
Jooyeon Lee, Se-Ran Yang
Organoid. 2021;1:e4.

Review Article

Feb 15, 2021
Disease modeling and drug screening using human airway organoids: a systematic review
Do Hyun Kim, Sung Won Kim
Organoid. 2021;1:e8.

Review Article

May 15, 2021

Organoid

Online ISSN: 2765-205X

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